In a one year old Bruna dels Pirineus breed cow multiple vesicular lesions were observed in the liver. Through microscopical obervation the vesicles showed no identifiable content.

Macroscopically the differential diagnosis of this type of lesion is:

  • Echinococcus granulosus: cestode parasite of the small intestine of carnivores (dogs). The metacestode stage or hydatid cyst can be found in ruminants, normally in the liver or lungs. It usually consists of a single cyst, which can reach a considerable size and contain hydatid sand (protoescolexs). The cyst may break generating multiple cysts. These cysts can degenerate and develop necrotic caseous lesions.
  • Echinococcus multilocularis: characterized by generating multiple cysts clusters , resembling grapes, as those seen in the image. It is a zoonosis since men can also act as intermediate hosts. This parasite is not endemic in Spain.
  • Serous or congenital hepatic cysts: believed to be originated in embryonic biliary ducts.
  • Cholangioma or biliary cystadenoma: bile duct neoplasm with cystic growth pattern, rarely described in ruminants.
Focal lesion, infiltrating the liver parenchyma, consisting of multiple vesicles with a serous or purulent content.

Focal lesion, infiltrating the liver parenchyma, consisting of multiple vesicles with a serous or purulent content.