In a hybrid breed pig of 6 months of age an increase in size of the kidneys was obserevd algon with the presence of colour changes on the renal surface. It consisted of red or black punctate lesions (petechiae) together with the presence of superficial cavities filled with liquid.

Histopathology evidenced the formation of multiple cavitary lesions in the parenchyma of the renal cortex. It also evidenced other lesions consistent with a porcine dermatitis and nephropathy syndrome (PDNS) in a resolution phase (proliferative necrotizing glomerulonephritis). Usually the PDNS also affects the skin (see hemorrhagic skin lesions and PDNS entries), but this is not always the case.

The presence of type 2 porcine circovirus genome was ruled out by in situ hybridization, this virus has been linked to this disease.

Increased kidney size, with petechiae and presence of cystic cavities.

When cut a reddish discoloration can be seen  in the renal cortex.