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Multifocal, multilobed whitish nodular lesions were observed in the liver of a 32-month-old goat.

Multifocal and multilobed lesions in a goat’s liver.

When sectioned, the lesions deepen in the parenchyma and its consistency is hardened and crackles when cut (mineralized).


What is your diagnosis? (90)


The lesions observed in the histopathological study consisted of multiple necrotizing lesions, with mineralization and abundant inflammatory infiltrate consisting of macrophages (granulomatous) with the presence of multinucleated giant cells with the nuclei distributed in a horseshoe-like fashion on the periphery (Langhans Cells). Ziehl Neelsen's staining made it possible to observe the presence of a few structures compatible with acid-alcohol-resistant bacilli within the the lesion.
These are lesions compatible with tuberculous granulomatous hepatitis, probably caused by Mycobacterium spp. Yet, macroscopically it was not possible to ascertain it, therefore, samples had to be sent in all cases to rule out tuberculosis.

The animal also had severe granulomatous pneumonia and granulomatous lymphadenitis.

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Question 1
What is your diagnosis?
Tuberculous granulomatous hepatitits
Hepatic carcinoma
Parasitic granulomatous hepatitis (C.tenuicollis)
Parasitic granulomatous hepatitis (Hydatidosis)
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